4D NucleomeTechnology - Resources - Data

4D Nucleome Aims to Understand the Principles Underlying Nuclear Organization

Working to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect both normal development and various diseases.

4D Nucleome Aims to Improve Public Health

The 4D Nucleome (4DN) Program explores the 3D organization of the DNA in the nucleus and how the organization changes over time (the fourth dimension). Exploring the 4D organization of DNA requires developing new tools to observe differences in the organization of DNA between different cells and how the genome organization in the nucleus of a single cell changes over time.
Program Overview

4DN Phase II Funded Research Announcements

The 3D Genome - Nature Reviews: Molecular Cell Biology

Mapping the Structure of Genomes in Space and Time

Check The Latest
4D Nucleome Publications

4D Nucleome Annual Meeting on December 9-11, 2023 at Boston Park Plaza, in Boston, MA. Registration will open on August 1 (4DN consortium members only)... Read more
July 28, 2023
Blake Nolan
“Multimodal Visualization for 4DN data using Nucleome Browser and OME” October 28, 2022 8AM – 9AM PST; Virtual on Zoom.... Read more
October 21, 2022
Blake Nolan
The 4DN Data Portal - Data, Resources and Tools to help elucidate nuclear organization in space and time... Read more
September 23, 2022
Blake Nolan
Lindsay Lee, Miao Yu, Xiaoqi Li, Chenxu Zhu, Yanxiao Zhang, Hongyu Yu, Ziyin Chen, Shreya Mishra, Bing Ren, Yun Li, Ming Hu... Read more
August 30, 2023
Asli Yildirim, Nan Hua, Lorenzo Boninsegna, Yuxiang Zhan, Guido Polles, Ke Gong, Shengli Hao, Wenyuan Li, Xianghong Jasmine Zhou & Frank Alber ... Read more
August 14, 2023
Lindsay Lee, Hongyu Yu, Bojing Blair Jia, Adam Jussila, Chenxu Zhu, Jiawen Chen, Liangqi Xie, Antonina Hafner, Shreya Mishra, Duan Dennis Wang, Caterina Strambio-De-Castillia, Alistair Boettiger, Bing Ren, Yun Li & Ming Hu ... Read more
August 12, 2023
Yang, X., Jones, I. R., Chen, P. B., Yang, H., Ren, X., Zheng, L., Li, B., Li, Y. E., Sun, Q., Wen, J., Beaman, C., Cui, X., Li, Y., Wang, W., Hu, M., Ren, B., Shen, Y.... Read more
August 30, 2023
Chiariello, A. M., Abraham, A., Bianco, S., Esposito, A., Vercellone, F., Conte, M., Fontana, A., Nicodemi, M.... Read more
July 28, 2023
Gao, V. R., Yang, R., Das, A., Luo, R., Luo, H., McNally, D. R., Karagiannidis, I., Rivas, M. A., Wang, Z.-m., Barisic, D., Karbalayghareh, A., Wong, W., Zhan, Y., Chin, C. R., Noble, W. S., Bilmes, J. A., Apostolou, E., Kharas, M., Beguelin, W., Viny, A. D., Huangfu, D., Rudensky,... Read more
July 28, 2023

Subscribe now

Give us a call or fill in the form below and we will contact you. We endeavor to answer all inquiries within 24 hours on business days.