4D NucleomeTechnology - Resources - Data

4D Nucleome Aims to Understand the Principles Underlying Nuclear Organization

Working to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect both normal development and various diseases.

4D Nucleome Aims to Improve Public Health

The 4D Nucleome (4DN) Program explores the 3D organization of the DNA in the nucleus and how the organization changes over time (the fourth dimension). Exploring the 4D organization of DNA requires developing new tools to observe differences in the organization of DNA between different cells and how the genome organization in the nucleus of a single cell changes over time.
Program Overview

4DN Phase II Funded Research Announcements

The 3D Genome - Nature Reviews: Molecular Cell Biology

Mapping the Structure of Genomes in Space and Time

Check The Latest
4D Nucleome News

The conference (August 21-23, 2023) will take place at the Beckman Center of the National Academies of Sciences & Engineering near the UC Irvine campus in Southern California and it will feature a 4DN workshop and additional events co-hosted by 4DN Consortium.... Read more
March 23, 2023
Blake Nolan
Save the date for the next 4D Nucleome Annual Meeting to be held in person on December 9-11, 2023 at Boston Park Plaza, in Boston, Massachusetts.... Read more
February 28, 2023
Blake Nolan
“Multimodal Visualization for 4DN data using Nucleome Browser and OME” October 28, 2022 8AM – 9AM PST; Virtual on Zoom... Read more
October 21, 2022
Blake Nolan
Mayank N. K. Choudhary, Kara Quaid, Xiaoyun Xing, Heather Schmidt & Ting Wang ... Read more
February 6, 2023
Parisha P. Shah, Kathleen C. Keough, Ketrin Gjoni, Garrett T. Santini, Richard J. Abdill, Nadeera M. Wickramasinghe, Carolyn E. Dundes, Ashley Karnay, Angela Chen, Rachel E. A. Salomon, Patrick J. Walsh, Son C. Nguyen, Sean Whalen, Eric F. Joyce, Kyle M. Loh, Nicole Dubois, Katherine S. Pollard & Rajan Jain ... Read more
January 23, 2023
Beth K. Martin, Chengxiang Qiu, Eva Nichols, Melissa Phung, Rula Green-Gladden, Sanjay Srivatsan, Ronnie Blecher-Gonen, Brian J. Beliveau, Cole Trapnell, Junyue Cao & Jay Shendure ... Read more
January 18, 2023
Jain, N., Goyal, Y., Dunagin, M. C., Cote, C. J., Mellis, I. A., Emert, B., Jiang, C. L., Dardani, I. P., Reffsin, S., Raj, A.... Read more
February 10, 2023

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