4D NucleomeTechnology - Resources - Data

4D Nucleome Aims to Understand the Principles Underlying Nuclear Organization

Working to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect both normal development and various diseases.

4D Nucleome Aims to Improve Public Health

The 4D Nucleome (4DN) Program explores the 3D organization of the DNA in the nucleus and how the organization changes over time (the fourth dimension). Exploring the 4D organization of DNA requires developing new tools to observe differences in the organization of DNA between different cells and how the genome organization in the nucleus of a single cell changes over time.
Program Overview

4DN Phase II Funded Research Announcements

The 3D Genome - Nature Reviews: Molecular Cell Biology

Mapping the Structure of Genomes in Space and Time

Check The Latest
4D Nucleome Publications

SAVE THE DATE! Wyndham San Diego Bayside Hotel (San Diego, CA) December 11-13, 2024... Read more
March 18, 2024
Blake Nolan
Are you an undergraduate with an interest in #genomics and #CellBiology? Check out the 2024 4DN summer undergraduate research internship opportunity and apply to work on cutting-edge research! Applications open 12/15 and close 2/16.... Read more
December 21, 2023
Blake Nolan
“Multimodal Visualization for 4DN data using Nucleome Browser and OME” October 28, 2022 8AM – 9AM PST; Virtual on Zoom.... Read more
October 21, 2022
Blake Nolan
Erica M. Hildebrand, Kirill Polovnikov, Bastiaan Dekker, Yu Liu, Denis L. Lafontaine, A. Nicole Fox, Ying Li, Sergey V. Venev, Leonid A. Mirny, Job Dekker... Read more
April 18, 2024
Allison Coté, Aoife O'Farrell, Ian Dardani, Margaret Dunagin, Chris CotéYihan Wan, Sareh Bayatpour, Heather L Drexler, Katherine A Alexander, Fei Chen, Asmamaw T Wassie, Rohan Patel, Kenneth Pham, Edward S Boyden, Shelly Berger, Jennifer Phillips-Cremins, L Stirling Churchman, Arjun Raj... Read more
April 5, 2024
Junhong Choi, Wei Chen, Hanna Liao, Xiaoyi Li,Jay Shendure... Read more
April 10, 2024
Leonid Andronov, Mengting Han, Yanyu Zhu, Ashwin Balaji, Anish R. Roy, Andrew E. S. Barentine, Puja Patel, Jaishree Garhyan, Lei S. Qi, W.E. Moerner... Read more
April 1, 2024
Daniel, B., Chen, A. Y., Sandor, K., Zhang, W., Miao, Z., Lareau, C. A., Yost, K. E., Chang, H., Satpathy, A.... Read more
March 4, 2024

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