4D NucleomeTechnology - Resources - Data

4D Nucleome Aims to Understand the Principles Underlying Nuclear Organization

Working to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect both normal development and various diseases.

4D Nucleome Aims to Improve Public Health

The 4D Nucleome (4DN) Program explores the 3D organization of the DNA in the nucleus and how the organization changes over time (the fourth dimension). Exploring the 4D organization of DNA requires developing new tools to observe differences in the organization of DNA between different cells and how the genome organization in the nucleus of a single cell changes over time.
Program Overview

4DN Phase II Funded Research Announcements

The 3D Genome - Nature Reviews: Molecular Cell Biology

Mapping the Structure of Genomes in Space and Time

Check The Latest
4D Nucleome Publications

SAVE THE DATE! Wyndham San Diego Bayside Hotel (San Diego, CA) December 11-13, 2024... Read more
March 18, 2024
Blake Nolan
Are you an undergraduate with an interest in #genomics and #CellBiology? Check out the 2024 4DN summer undergraduate research internship opportunity and apply to work on cutting-edge research! Applications open 12/15 and close 2/16.... Read more
December 21, 2023
Blake Nolan
“Multimodal Visualization for 4DN data using Nucleome Browser and OME” October 28, 2022 8AM – 9AM PST; Virtual on Zoom.... Read more
October 21, 2022
Blake Nolan
Meng Xu, Dulmi Senanayaka, Rongwei Zhao, Tafadzwa Chigumira, Astha Tripathi, Jason Tones, Rachel M. Lackner, Anne R. Wondisford, Laurel N. Moneysmith, Alexander Hirschi, Sara Craig, Sahar Alishiri, Roderick J. O’Sullivan, David M. Chenoweth, Nicholas J. Reiter & Huaiying Zhang ... Read more
March 9, 2024
Chan-I. Chung, Junjiao Yang, Xiaoyu Yang, Hongjiang Liu, Zhimin Ma, Frank Szulzewsky, Eric C. Holland, Yin Shen, and Xiaokun Shu... Read more
February 5, 2024
Daniel, B., Chen, A. Y., Sandor, K., Zhang, W., Miao, Z., Lareau, C. A., Yost, K. E., Chang, H., Satpathy, A.... Read more
March 4, 2024
Zhao, R., Xu, M., Wondisford, A. R., Lackner, R. M., Salsman, J., Dellaire, G., Chenoweth, D. M., O'Sullivan, R. J., Zhao, X., Zhang, H.... Read more
February 29, 2024
Chandrashekar, H., Simandi, Z., Choi, H., Ryu, H.-S., Waldman, A. J., Nikish, A., Muppidi, S. S., Gong, W., Paquet, D., Phillips-Cremins, J. E.... Read more
February 27, 2024

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