4D NucleomeTechnology - Resources - Data

4D Nucleome Aims to Understand the Principles Underlying Nuclear Organization

Working to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect both normal development and various diseases.

4D Nucleome Aims to Improve Public Health

The 4D Nucleome (4DN) Program explores the 3D organization of the DNA in the nucleus and how the organization changes over time (the fourth dimension). Exploring the 4D organization of DNA requires developing new tools to observe differences in the organization of DNA between different cells and how the genome organization in the nucleus of a single cell changes over time.
Program Overview

4DN Phase II Funded Research Announcements

The 3D Genome - Nature Reviews: Molecular Cell Biology

Mapping the Structure of Genomes in Space and Time

Check The Latest
4D Nucleome Publications

Are you an undergraduate with an interest in #genomics and #CellBiology? Check out the 2024 4DN summer undergraduate research internship opportunity and apply to work on cutting-edge research! Applications open 12/15 and close 2/16.... Read more
December 21, 2023
Blake Nolan
4D Nucleome Annual Meeting on December 9-11, 2023 at Boston Park Plaza, in Boston, MA. Registration will open on August 1 (4DN consortium members only)... Read more
July 28, 2023
Blake Nolan
“Multimodal Visualization for 4DN data using Nucleome Browser and OME” October 28, 2022 8AM – 9AM PST; Virtual on Zoom.... Read more
October 21, 2022
Blake Nolan
Radhika Mathur, Qixuan Wang, Patrick G. Schupp, Ana Nikolic, Stephanie Hilz, Chibo Hong, Nadia R. Grishanina, Darwin Kwok, Nicholas O. Stevers, Qiushi Jin, Mark W. Youngblood, Lena Ann Stasiak, Ye Hou, Juan Wang, Takafumi N. Yamaguchi, Marisa Lafontaine, Anny Shai, Ivan V. Smirnov, David A. Solomon, Susan M. Chang, Shawn... Read more
January 18, 2024
Xingjie Ren, Han Yang, Jovia L. Nierenberg, Yifan Sun, Jiawen Chen, Cooper Beaman, Thu Pham, Mai Nobuhara, Maya Asami Takagi, Vivek Narayan, Yun Li, Elad Ziv, and Yin Shen... Read more
December 21, 2023
Li, G., Kim, H.-J., Pendyala, S., Zhang, R., Disteche, C. M., Vert, J.-P., Deng, X., Fowler, D. M., Noble, W. S.... Read more
January 26, 2024
Gilbertson, E. N., Brand, C. M., McArthur, E., Rinker, D. C., Kuang, S., Pollard, K. S., Capra, J. A.... Read more
December 23, 2023

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