4D NucleomeTechnology - Resources - Data

4D Nucleome Aims to Understand the Principles Underlying Nuclear Organization

Working to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect both normal development and various diseases.

4D Nucleome Aims to Improve Public Health

The 4D Nucleome (4DN) Program explores the 3D organization of the DNA in the nucleus and how the organization changes over time (the fourth dimension). Exploring the 4D organization of DNA requires developing new tools to observe differences in the organization of DNA between different cells and how the genome organization in the nucleus of a single cell changes over time.
Program Overview

4DN Phase II Funded Research Announcements

The 3D Genome - Nature Reviews: Molecular Cell Biology

Mapping the Structure of Genomes in Space and Time

Check The Latest
4D Nucleome Publications

SAVE THE DATE! Wyndham San Diego Bayside Hotel (San Diego, CA) December 11-13, 2024... Read more
March 18, 2024
Blake Nolan
Are you an undergraduate with an interest in #genomics and #CellBiology? Check out the 2024 4DN summer undergraduate research internship opportunity and apply to work on cutting-edge research! Applications open 12/15 and close 2/16.... Read more
December 21, 2023
Blake Nolan
“Multimodal Visualization for 4DN data using Nucleome Browser and OME” October 28, 2022 8AM – 9AM PST; Virtual on Zoom.... Read more
October 21, 2022
Blake Nolan
Han Zhao, Yinzhi Lin, En Lin, Fuhai Liu, Lirong Shu, Dannan Jing, Baiyue Wang, Manzhu Wang, Fengnian Shan, Lin Zhang, Jessica C. Lam, Susannah C. Midla, Belinda M. Giardine, Cheryl A. Keller, Ross C. Hardison, Gerd A. Blobel & Haoyue Zhang... Read more
Andrea M Chiariello, Alex Abraham, Simona Bianco, Andrea Esposito, Andrea Fontana, Francesca Vercellone, Mattia Conte , Mario Nicodemi... Read more
Karolina Jodkowska, Zofia Parteka-Tojek, Abhishek Agarwal, Michał Denkiewicz, Sevastianos Korsak, Mateusz Chiliński, Krzysztof Banecki, Dariusz Plewczynski... Read more
May 20, 2024
Derek J. Le, Antonina Hafner, Sadhana Gaddam, Kevin C. Wang, Alistair N. Boettiger... Read more
May 10, 2024
Chuanbin Su, Keerthivasan Raanin Chandradoss, Thomas Malachowski, Ravi Boya, Han-Seul Ryu, Kristen J. Brennand, Jennifer E. Phillips-Cremins... Read more
May 2, 2024

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