Education and Outreach

This is a list of past and up-coming conferences and tutorial material advertising 4DN progress with workshops and scientific talks. If you have any suggestion please contact us sending an email to

Tutorial Materials

Tutorial for 4DN new members

Welcome to 4DN! Watch this video on YouTube to learn how to use 4DN tools and services!

4DN YouTube Channel

Official 4D Nucleome YouTube channel. Webinars, workshops and other 4DN-related videos are posted. Subscribe to the channel!

4DN Investigator Featured on "Science Happens!"

In Episode 5 of "Science Happens", named : "Everything you thought you knew about the shape of DNA is wrong". Watch Dr. Job Dekker describe how the folding of DNA strands holds cues to human health here.

Conversations: A Guide to Packing Your DNA

Genetic material is not randomly organized within the nucleus of a cell. How this organization occurs and why it matters are questions that Cell editor Marta Koch posed to Mitchell Guttman, Job Dekker, and Stavros Lomvardas. The 4D Nucleome grantees Drs. Job Dekker, Mitchell Guttman, and Stavros Lomvardas discuss the organization of genetic material in the nucleus, how it occurs, and why it matters.

A quick guide to 4DN visualization software

Plot a course through the genome: inspired by Google Maps, a suite of tools is allowing researchers to chart the complex conformations of chromosomes.

Hi-C Data Analysis Bootcamp

A tutorial on measuring, analyzing, and visualizing the 3D genome with Hi-C provided by Harvard, MIT, and UMassMed (Burak Alver, Nils Gehlenborg and Peter Park).

TechBlog: HiPiler simplifies chromatin structure analysis

A blog post about the software HiPiler from Nils Gehlenborg Lab published on Nature.

Up-coming workshops and conferences

Keystone Symposia: Higher-Order Chromatin Architecture in Time and Space(Click here for registration)

When: November 15-17, 2021. 10AM EST.
Where: Virtual Meeting
Scientific Organizers: Jennifer E. Phillips-Cremins, Job Dekker and Stavros Lomvardas

Past workshops and conferences

Second Annual Meeting on Advances on Nuclear Topology and 3D Chromatin Architecture in Cancer (Click here for free registration)

When: September 24, 2021
Where: Virtual on Zoom
Scientific Organizers: Jane Skok, Iannis Aifantis, Ari Melnick

Higher-Order Chromatin Architecture in Time and Space

The 2020 Keystone meeting is meant to highlight new frontiers across disciplines in tackling the dynamics and functional roles of the 3D genome in cellular functions across time and space in development and disease. The conference program will also include workshops on: (1) Leading computational methods to identify biologically relevant patterns in Hi-C data, (2) New genome mapping and imaging technologies, and (3) New data resources available through the 4D Nucleome consortium. Finally, it will conclude with a session devoted to novel tools for imaging and engineering the 3D genome.
When: March 15 - 19, 2020
Where: Whistler Conference Centre, Whistler, BC, Canada
Scientific Organizers: Jennifer E. Phillips-Cremins, Job Dekker and Stavros Lomvardas

The Four-Dimensional Genome

This symposium will bring together latest advances in the fields of genomics, microscopy and modelling to foster their integration towards a comprehensive spatial and temporal understanding of the functional four-dimensional organisation of the eukaryotic genome.
When: Mar 29 - Apr 1, 2020
Where: EMBL Heidelberg, Germany
Organizers: Wendy Bickmore, Jan Ellenberg, Susan M. Gasser, Christian Haring, Bas van Steensel, Tim Nurnberger.

2019 4DN-ASCB Satellite Meeting

Bridging the 4D Genome with Cell Biology
When: December 5-6, 2019
Where: Capital Hilton, Washington, D.C.
Meeting Committee Chairs: Jennifer Phillips-Cremins, Bing Ren, Sheng Zhong

Long-Read Sequencing Workshop

When: September 17-20, 2019
Where: The Jackson Laboratory for Genomic Medicine, Farmington, CT
Organizers: Chia-Lin Wei, Rachel Goldfeder

2019 Gordon Research Conference

Genome Architecture in Cell Fate and Disease: The Eukaryotic Genome in 4 Dimensions: Integrative Approaches to Bridging Genotype and Phenotype
When: August 4-9, 2019
Where: The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong
Organizers: Dave Gilbert, Yijun Ruan, Victor Corces and Danny Leung

2020 FASEB meeting on Nuclear Bodies

When: July 26-31, 2019
Where: Oak island Resort and Conference Center, Nova Scotia, Canada
Organizers: Paul Kaufman, Karla Neugebauer, Thoru Pederson

François Jacob Conference

Evolution, Structure and Function of Chromosomes High Order Structure
When: June 4-7, 2019
Where: Institute Pasteur, Paris, France

Southwestern Bioinformatics Conference

When: May 31, 2019
Where: Sanford Consortium, San Diego, CA

Biophysical Society Annual Meeting

63rd Annual Meeting of the Biophysical Society
When: March 2-6, 2019
Where: Baltimore, Maryland, USA

2019 Keystone Symposia

3D Genome: Gene Regulation and Disease
When: March 17-21, 2019
Where: Fairmont Banff Springs, Banff, Alberta, Canada
Scientific Organizers: Bing Ren, Ana Pombo and Joseph R. Ecker

2019 Gordon Research Conference

How Alterations in DNA Sequence and Chromatin Modifications Impact Cancer Etiology and Therapy
When: April 7-12, 2019
Where: Renaissance Tuscany Il Ciocco, Lucca (Barga), Italy
Chair: Jonathan D. Licht; Vice Chair: Ting Wang

2019 Keystone Symposia

Biomolecular Condensates: Phase-Separated Organizers of Cellular Biochemistry
When: April 10-13, 2019
Where: Snowbird Resort, Snowbird, Utah, USA
Scientific Organizers: Michael K. Rosen and Anthony Hyman

2018 4DN-ASCB Satellite Meeting: bridging the 4D Genome with Cell Biology

When: December 7, 2018
Where: Marriott Marquis San Diego Marina, San Diego, CA, USA
Organizers: Bing Ren, Sheng Zhong, Ana Pombo, Jennifer Phillips-Cremins, Thoru Pederson, Ting Wang

Centromere Biology - 2018 Gordon Research Conference

When: July 29 - August 3, 2018
Where: Mount Snow Resort, West Dover, Vermont, USA
Organizers: Aaron Straight and Sylvia Erhardt

Chromatin Architecture and Chromosome Organization

When: March 23-27, 2018
Where: Whistler, British Columbia, Canada
Scientific Organizers: Edith Heard and Peter Fraser

DNA and RNA Methylation

When: January 21-25, 2018
Where: Fairmont Hotel Vancouver, Vancouver, British Columbia, Canada
Scientific Organizers: Chuan He and Ting Wang, January 22th
Workshop on "Epigenome and Computational Biology" hosted by Dr Ting Wang

Program in Quantitative Genomics (PQG) 11th Annual Conference

When: November 1-2, 2017
Where: Joseph B. Martin Conference Center at Harvard Medical School in Boston, MA
Co-organized by Peter Park
KEYNOTE SPEAKERS: Bradley Bernstein (Mass General Hospital), Wouter de Laat (Hubrecht Institute), William Greenleaf (Stanford University)
SPEAKERS: Erez Lieberman Aiden (Baylor College of Medicine), Nils Gehlenborg (Harvard Medical School), Francesco Ferrari (FIRC Institute of Molecular Oncology), Luca Giorgetti (Friedrich Miescher Institute), Ana Pombo (Max Delbrück Center for Molecular Medicine), Kikue Tachibana-Konwalski (Austrian Academy of Sciences), Ting Wu (Harvard Medical School), Feng Yue (Pennsylvania State University), Xiaowei Zhuang (Harvard Medical School)

Integrated Approaches for Spatial and Temporal Mapping of Gene Activity in Cells and Tissues

When: September 20, 2017, Bethesda
The purpose of this workshop is to introduce expertise and technology to the consortium that would be important to help achieve the 4DN goals. The workshop will focus on spatial and temporal aspects of chromatin structure that lead to activation. The goal would be to: 1) identify areas of collaboration for the 4DN network, 2) identify potential areas of collaboration with other programs, 3) provide an opportunity to have a dialog between 4DN investigators and other researchers working in this field.

ISMB Tutorial: 3D Genome Data Processing, Analysis, and Visualization

When: July 21, 2017, Prague
Offered by 4DN members: Leonid Mirny, Nils Gehlenborg, and Jian Ma
Goals and Objectives: 1) To introduce the theoretical concepts related to 3D genome data analysis, 2) To familiarize participants with the data types, analysis pipeline, and common tools for analysis and visualization of 3D genome data, 3) To provide a hands on experience in data analysis by walking through some common use cases of existing tools for data analysis and visualization.

Gordon Research Conference: Genome Architecture in Cell Fate & Disease

When: July 2-7, 2017
  • Structure of the Nucleus (Wange Lu / Thomas Misteli)
  • 3D Nuclear Structure and Human Diseases (Peter Fraser / Rafael Casellas / Martin Hetzer)
  • Cancer Epigenome (Thomas Misteli / Bing Ren)
  • Epigenome, Chromatin Structure and Gene Transcription (Yijun Ruan / Joanna Wysocka / Wouter De Laat)
  • Non-Coding RNA and Chromatin Structure (Rafael Casellas / Mitch Guttman / Peter Fraser)
  • Tools and Technology to Study 4D Nucleome (David Gilbert / Kazuhiro Maeshima / Jane Skok)

Workshop on Chromatin Interaction Analysis by Paired-End Tag Sequencing (ChIA-PET)

Presenters: The Jackson Laboratory for Genomic Medicine
When: 11/7/16-11/7/16

WashU Epigenome Browser @ Keystone Symposia 2016

Presenters: Ting Wang
Where: 2016 Keystone Symposia, Chromatin and Epigenetics (C2)
When: 3:30-4:30pm 3/21/16

A Toxicology User's Guide to the Roadmap Epigenomics and ENCODE Data Resources

Presenters: Ting Wang, Feng Yue, Lisa Chadwick, Daniel Gilchrist, Shaun McCullough, and Terry Furey
Where: SOT 2016 Satellite Meeting
When: 1:00-6:00pm 3/17/16

Workshop on 3D Genome Mapping Technology

Presenters: Rafael Casellas, Melissa Fullwood, James Noonan, Yijun Ruan, Chia-Lin Wei, and Michael Q. Zhang
When: 11/10/14-11/4/14